APP/PS1 Idol−/− mice and APP/PS1 Idol+/+ mice

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APPswe/PSEN1dE9 mice on a C57BL/6 background (APP/PS1
mice)  Idol−/− mice (13) were backcrossed to C57BL/6 mice for eight generations before mating to APP/PS1
mice.

$500.00

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These are the Idol knockout mouse to study the functions of Idol genes. The E3 ubiquitin ligase Idol controls brain LDL receptor
expression, ApoE clearance, and Ab amyloidosis.

The E3 Ubiquitin Ligase Idol Controls Brain LDL Receptor Expression, ApoE Clearance, and Aβ Amyloidosis

J Choi et al.  Sci Transl Med (2015)

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